Directed and co-written by Douglas Buck, this remake of Sisters starts with developmental psychologist Dr. Philip Lacan (Stephen Rea) performing magic at a children’s party being thrown at his work, the Zurvan Institute. His ex-wife — and former patient — Angelique (Lou Doillon) — is his assistant, but the party gets weird when Grace Collier (Chloë Sevigny), a reporter, is found and kicked out. 

Dr. Dylan Wallace (Dallas Roberts) ends up having a one-night stand with Angelique, learning that it’s her birthday, as well as the birthday of her roommate and twin sister, Annabel. He goes to get them a birthday cake, just in time to be stabbed with knitting needles by Annabel, which Grace sees on Phillip’s computer as she snoops on him.

Grace is against Phillip, as her mother was committed to a psychiatric hospital. She’s sure that he’s using psychotropic drugs on both Angelique and Annabel, as well as covering up their crimes. A former assistant, Dr. Mercedes Kent (Gabrielle Rose), reveals that Angelique and Annabel were conjoined twins who were taken by their mother from Canada to France, where they worked in a sideshow. Angelique was the quiet one; Annabel was murderous; they were separated, and it’s thought that Annabel died of lung failure and Angelique lives alone under Philip’s supervision.

As she sneaks into the institute, Grace is captured by Phillip, who drugs her, and the revelations of what really happened appear as if they were dreams. Philip started a sexual affair with Angelique when she still had a twin, so he said that Annabel was a parasite. He performed the separation so he could be with her, but after Annabel died, Angeliqiue took on her need to kill. Grace is so drugged out that she stabs the doctor, then Angelique kills Grace’s co-worker Larry (JR Bourne) before giving Grace a matching scar and making her her new sister.

Buck said, “In the original film, which I love, De Palma chose style over substance. I’m interested in exploring all the other stuff that’s there — the perversity, the tragedy, the sadness. All those character traits make it, to me, more interesting. I want to make the characters more alive.” I think that he did a great job here, as this can stand on its own.

You can watch this on Tubi.