Based on the novel The Disorientated Man by Peter Saxon*, this Amicus film boasts the best line-up potentially ever in a horror film. It features the iconic Christopher Lee, the legendary Peter Cushing, and the master of macabre Vincent Price, all delivering stellar performances.

The film opens with a man jogging, collapsing, and waking up in a hospital, missing his leg. He screams, and then the same scream repeats as he loses every appendage. Meanwhile, an Eastern European spy named Konratz (played by Marshall Jones, Cry of the Banshee) is on a killing spree, targeting his superiors, including Cushing. In another subplot, someone is killing young women in London, and it appears that Keith (Michael Gothard) is the murderer, a blood-drinking super-strong weirdo.

Price shows up as the sinister Dr. Browning, and it all ends up being a conspiracy movie that owes a fair deal to Invasion of the Body Snatchers. However, that movie didn’t end with much of its cast falling into acid.

According to Lee, the villains of this movie were going to be revealed as aliens, but that was cut out for some reason, leaving a lot of the movie unexplained.

This was directed by Gordon Hessler (Pray for Death; Scream, Pretty Peggy; Kiss Meets the Phantom of the Park, The Golden Voyage of Sinbad).

Team Price, Lee, and Cushing appear in only one other movie: House of the Long Shadows. They barely appear in any scenes together, though.

*A house pen name for multiple authors at Amalgamated Press; the Saxon that wrote this story is Stephen Frances, edited by W. Howard Baker.

Source

Film Still Scream and Scream Again Peter Cushing Christopher Lee 1970 – Richard Thornton Books. https://richardthorntonbooks.com/product/film-still-scream-and-scream-again-peter-cushing-christopher-lee-1970/