One year after the explosion of Flight 180, Kimberly Corman (A.J. Cook, The Virgin Suicides), Shaina McKlank (Sarah Carter), Dano Estevez (Alex Rae) and Frankie Whitman (Shaun Sipos) are saved from a multiple car pile-up when her vision keeps all the cars behind her from entering the freeway. As a cop interrogates her, her friends are killed in the eventual pileup. Now, Death is after everyone. Again.
Kimberly finds Clear Rivers (Ali Larter), the last survivor of Flight 180, who is hiding from death inside a psychiatric ward (it’s the same location that was Smith’s Grove in Halloween: Resurrection) after Alex Browning’s (Devon Sawa, who doesn’t even show up) off-screen death. She introduces her to William Bludworth (Tony Todd), who informs her that only new life can stop what Death wants.
Soon, everyone is dying in reverse of the order they were originally to croak and the gore has been upped considerably from the last movie. The car crash at the open of the film is enough to keep anyone from getting behind the wheel.
It was directed by David R. Ellis, who also did the last film in this series and Snakes on a Plane. He was also a child actor with Kurt Russell in several Disney films before becoming a stuntman and second unit director.